Multimodal Analgesia Versus Routine Care Pain Management
Stopped early · Not applicable
Conditions studied: Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
In brief
Most patients undergoing surgery experience significant post-operative pain. Inadequate peri-operative pain management may decrease post-operative mobilization and increase length of hospitalization. Additionally, poorly managed acute post-operative pain analgesia is associated with an increased risk of developing chronic pain and delayed wound healing. Lumbar spine surgery is particularly painful, often requiring a multi-day hospitalization. The most common post-operative analgesia used in spine surgery is narcotic medication delivered via an intravenous patient controlled analgesia (IV PCA). A multimodal peri-operative pain management protocol for spine surgery has the potential to not only decrease pain but also to improve recovery, decrease narcotic consumption, decrease length of stay in the hospital and reduce both direct and indirect hospital costs. The purpose of this study is to determine if post-operative pain and rate of recovery are improved in patients undergoing spine surgery using MMA compared to usual analgesic care.
Key facts
- Study ID
- NCT01861743
- Run by
- Rush University Medical Center
- People needed
- 42
- Starts
- 2013-04-01
- Expected to finish
- 2017-12-01
- Last updated by the study team
- 2018-08-29
Who can join
Age: any. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients undergoing single level MIS-TLIF
- Patients able to provide informed consent
You may not qualify if…
- Allergies or other contraindications to medicines in the protocol
- Current liver disease with documented liver function test abnormality
- Current renal disese with documented glomerular filtration rate (GFR) < 60 mL/min/1.73m2
- Baseline (pre-operative) opioid use greater than 30 mg of morphine equivalents/day
- Active alcohol dependence
- Active illicit drug dependence
Where it is running
- Rush University Medical Center-Orthopedic Spine — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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