Critical Respiratory Events in Children Requiring Naloxone: Naloxone Use as Opioid Safety Measure

Completed

Conditions studied: Opioid Induced Respiratory Depression

In brief

Opioids are the mainstay of analgesia in hospitalized children but opioid therapy is associated with life-threatening respiratory depression requiring antagonism with naloxone. Hence, it is hypothesized that naloxone requirement can be used as a quality measure of opioid safety. A retrospective medical chart review of 95 patients, who received naloxone for life threatening events, from June 2006-2012, is planned, to identify significant factors associated with risk for opioid induced respiratory depression and formulation of preventive strategies.

Key facts

Study ID

NCT01860885

Run by

Children's Hospital Medical Center, Cincinnati

People needed

95

Starts

2012-08-01

Expected to finish

2013-05-01

Last updated by the study team

2013-05-23

Who can join

Age: 0 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• any gender, age or race
• administered naloxone for opioid induced respiratory depression

You may not qualify if…

• Any one who did not require naloxone for opioid induced respiratory depression

Where it is running

• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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