Nutrigenomics: Personalizing Weight Loss for Obese Veterans

Completed · Not applicable

Conditions studied: Obesity

In brief

This study aims to determine if providing genomic information to veterans can help them lose weight compared to usual care.

Key facts

Study ID

NCT01859403

Run by

University of California, San Diego

People needed

51

Starts

2012-11-01

Expected to finish

2014-03-01

Last updated by the study team

2021-04-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Veterans able to receive care at the VASDHS and planning to start the MOVE! program.
• Veterans able to understand and consent to the study.
• BMI equal to or greater than 30 kg/m2.

You may not qualify if…

• Veterans unable to receive care at the VASDHS.
• Veterans unable to understand the consent process at the discretion of the PI.
• Active substance abuse or substance dependence disorder
• Cognitive disorder, psychiatric hospitalization in past 6-months, or presence of suicidal ideation identified on self-report instruments
• Bradycardia, rapid heart rate or other arrhythmia or active ischemia by EKG.
• Uncontrolled thyroid disease as measured by a TSH above or below the normal range.
• Body mass index < 30 kg/m2.
• Chronic kidney disease stage III or higher by National Kidney Foundation criteria (GFR = 30-59 ml/min).
• New York Heart Association's functional classification of congestive heart failure above Class I (not limited with normal physical activity by symptoms; Class II occurs when ordinary physical activity results in fatigue, dyspnea, or other symptoms).
• Sodium or potassium outside the normal range.
• Edema requiring the use of daily diuresis with furosemide, bumex or other diuretic (does not include hydrochlorthiazide).
• The use of high dose oral corticosteroids (above replacement doses).
• Veterans deficient in 25-OH vitamin D (<20 units/dl).
• Veterans with fasting LDL > 190 mg/dl.
• Veterans with fasting triglyceride levels > 1000 mg/dl.
• Excessive caffeine use (>6 caffeinated beverages/days).
• Prior gastrointestinal surgery with the exception of distal appendectomy.
• Acute infections or current use of antibiotic therapy.

Where it is running

• VA San Diego Healthcare System — San Diego, California, United States

Full record on ClinicalTrials.gov

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