Adherence Enhancement for Renal Transplant Patients

Completed · Not applicable

Conditions studied: Renal Failure, Medication Adherence, Hypertension

In brief

Despite significant advances in the care of kidney transplant recipients, long term graft survival after renal transplantation remains suboptimal. Medication nonadherence and clinical inertia are key contributors to graft loss. The purpose of the proposed RCT feasibility study is to evaluate impact of a "bundled" wireless real time medication reminder system and blood pressure monitoring system in combination with a cognitive behavioral adherence skills enhancement program upon medication adherence, therapeutic drug concentration, and blood pressure, in nonadherent kidney transplant recipients with hypertension. We propose to recruit 60 kidney transplant recipients in phase 1 with 20 non-adherent continuing to phase 2 for a 5-month feasibility RCT.

Key facts

Study ID

NCT01859273

Run by

Medical University of South Carolina

People needed

18

Starts

2011-09-01

Expected to finish

2013-08-01

Last updated by the study team

2016-06-10

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Persons > 21 years of age
• first time recipient of a solitary kidney transplant
• prescribed at least 3 medications for immunosuppression and hypertension
• previous history of non-adherence
• functioning kidney transplant
• ability to speak, hear and understand English
• able to use medication delivery device and self administer medications
• able to operate blood pressure monitor
• comfortable using cell phone
• no other diagnosis that might shorten lifespan
• transplant physician's assent that the patient can participate

You may not qualify if…

• failure to meet all inclusion criteria

Where it is running

• Medical University of South Carolina — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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