The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study

Completed

Conditions studied: Glaucoma, Open-Angle, Eye Diseases

In brief

This study is designed to investigate whether the pupil response to slowly flashing colored lights is significantly altered in patients with glaucoma, as compared to a control group of subjects without glaucoma.

Key facts

Study ID

NCT01857440

Run by

Ohio State University

People needed

32

Starts

2013-05-01

Expected to finish

2015-12-01

Last updated by the study team

2017-09-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18+ years old
• Diagnosed with glaucoma of known severity (cases only)
• Have a refractive error between +4.00 and -8.00 sphere power, and no more than 3.00 diopters of astigmatism
• Best corrected visual acuity of 20/40 or better in each eye
• Have open anterior chamber angles

You may not qualify if…

• Diagnosis of glaucoma of a type other than Primary Open Angle (cases only)
• History of having surgery or taking medications known to profoundly affect pupillary function or shape
• Visual Field defect (controls only)
• History of traumatic brain injury requiring hospitalization
• Pregnancy
• History of optic nerve disease other than glaucoma
• History of retinopathy
• History of unreactive pupils
• Presence of significant cataract

Where it is running

• OSU College of Optometry — Columbus, Ohio, United States
• Havener Eye Institute — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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