Ohio Colorectal Cancer Prevention Initiative

Completed · Not applicable

Conditions studied: Lynch Syndrome, Colorectal Cancer

In brief

The purpose of the Ohio Colorectal Cancer Prevention Initiative (OCCPI) is to reduce morbidity and mortality due to colorectal cancer (CRC) in the state of Ohio. By identifying individuals at high-risk for CRC (genetically predisposed) and providing screening recommendations for cancer risk reduction, the OCCPI will understand how to increase length of life and quality of life for those diagnosed with CRC in Ohio, as well as to better prevent CRC in others in Ohio. Participants will have free tumor screening for Lynch syndrome, and may be eligible for free genetic testing and free genetic counseling as part of this study.

Key facts

Study ID

NCT01850654

Run by

Ohio State University Comprehensive Cancer Center

People needed

3470

Starts

2012-12-26

Expected to finish

2018-01-02

Last updated by the study team

2018-06-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Newly diagnosed with colorectal adenocarcinoma (all stages) and have a resection at any hospital in Ohio between 1/1/2013 and 12/31/2016.
• For individuals who have neoadjuvant treatment and show a complete response at resection, the tumor screening will be attempted on their original biopsy (even if it occurred in 2012) as long as their resection occurred between 1/1/2013 and 12/31/2016.
• Many individuals with stage IV CRC will not have a resection; therefore, the tumor screening will be attempted on their original colon biopsy as long as their primary diagnosis occurred between 1/1/2013 and 12/31/2016. If only metastatic CRC is available on a biopsy (liver or lymph node metastases), tumor screening will be attempted on the metastatic tissue.
• Newly diagnosed with endometrial cancer (any histology except sarcoma) and have a resection between 1/1/2013 and 12/31/2016 at OSU only.
• All at-risk relatives of the participants found to have LS.
• First-degree relatives (parents, siblings and adult children ≥ 25 years of age) of the CRC participants who do not have LS.

You may not qualify if…

• Prisoners.
• Individuals who are under the age of 18.
• Individuals must have a primary colorectal or endometrial cancer, not a recurrence of a previous colorectal or endometrial cancer.

Where it is running

• Akron General Medical Center — Akron, Ohio, United States
• Akron City/St. Thomas Hospital (Summa Health System) — Akron, Ohio, United States
• Summa Barberton (Summa Health System) — Barberton, Ohio, United States
• Mercy Clermont — Batavia, Ohio, United States
• Mercy Medical Center — Canton, Ohio, United States
• Aultman Hospital — Canton, Ohio, United States
• Adena Health System — Chillicothe, Ohio, United States
• The Christ Hospital — Cincinnati, Ohio, United States
• Good Samaritan Hospital (TriHealth) — Cincinnati, Ohio, United States
• Bethesda North Hospital (TriHealth) — Cincinnati, Ohio, United States
• Mercy Anderson — Cincinnati, Ohio, United States
• Mercy West — Cincinnati, Ohio, United States
• The Jewish Hospital — Cincinnati, Ohio, United States
• MetroHealth — Cleveland, Ohio, United States
• Fairview Hospital — Cleveland, Ohio, United States
• Cleveland Clinic — Cleveland, Ohio, United States
• Mount Carmel East Hospital — Columbus, Ohio, United States
• Riverside Methodist Hospital — Columbus, Ohio, United States
• Grant Medical Center — Columbus, Ohio, United States
• Mount Carmel West Hospital — Columbus, Ohio, United States
• Doctors Hospital — Columbus, Ohio, United States
• Summa Western Reserve (Summa Health System) — Cuyahoga Falls, Ohio, United States
• Miami Valley Hospital — Dayton, Ohio, United States
• Good Samaritan Hospital Dayton — Dayton, Ohio, United States
• Kettering Medical Center — Dayton, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.