Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults

Completed · Not applicable

Conditions studied: Muscle Synthesis

In brief

During aging there is a tendency for muscle protein synthesis (growth) to become less efficient and the resulting consequence leads to reduced muscle mass (sarcopenia) which can affect strength and mobility. Protein consumption may be one opportunity to alleviate this problem especially when consumed in appropriate amounts following resistance training. This study is designed to determine if a soy dairy protein blend, shown to be effective in younger adults, will produce beneficial muscle protein synthesis in older healthy adults following resistance exercise.

Key facts

Study ID

NCT01847261

Run by

DuPont Nutrition and Health

People needed

20

Starts

2013-04-01

Expected to finish

2014-12-01

Last updated by the study team

2019-10-07

Who can join

Age: 55 and older, up to 70. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• 55-70 yr olds Stable Body weight

You may not qualify if…

• Exercise training (>2 weekly sessions of moderate to high intensity aerobic or resistance exercise)
• Significant heart, liver, kidney, blood, respiratory disease or thyroid issues
• Peripheral vascular disease
• Orthopedic injury that prohibits participation in the exercise training
• Diabetes mellitus or other untreated endocrine disease
• Active cancer (all groups) and history of cancer
• Acute infectious disease or history of chronic infections (e.g. TB, hepatitis, HIV, herpes)
• Neurologic Injury or disease
• Recent (within 6 months) treatment with anabolic steroids, or corticosteroids.
• Alcohol or drug abuse
• Tobacco use (smoking or chewing)
• Malnutrition (BMI < 20 kg/m2, hypoalbuminemia, and/or hypotransferrinemia)
• Obesity (BMI > 30 kg/m2)
• Low hemoglobin levels (below normal values)
• Food allergies
• Taking dietary supplements such as green tea, omega 3 fatty acids, etc.
• Females

Where it is running

• University of Texas Medical Branch — Galveston, Texas, United States

Full record on ClinicalTrials.gov

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