In Vitro Maturation (IVM) of Human Oocytes
Withdrawn before enrolling · Not applicable
Conditions studied: Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins, Ovarian Hyper Stimulation Syndrome (OHSS)
In brief
We hypothesize that the combination of natural cycle IVF or low dose gonadotropin injection combined with In Vitro Maturation (IVM) (Natural IVF/IVM) is a viable option for a selected population of infertility patients who cannot tolerate exogenous gonadotropins or are at risk of ovarian hyperstimulation syndrome.
Key facts
- Study ID
- NCT01843569
- Run by
- Northwell Health
- People needed
- 0
- Starts
- 2015-01-01
- Expected to finish
- 2020-12-01
- Last updated by the study team
- 2020-11-16
Who can join
Age: 25 and older, up to 42. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Each subject must be female.
- Each subject must have an indication for COH and IVF or ICSI.
- Each subject must be willing and able to provide written informed consent for the trial.
- Each subject must be ≤42 years of age at the time of signing informed consent.
- Each subject must have a normal cervical smear result (no atypical or abnormal cells, or in case of atypical squamous or glandular cells, no signs of malignancy; corresponding to Papanicolaou [PAP] I or II) obtained within 12 months prior to signing informed consent must be available.
You may not qualify if…
- Subject with premature ovarian failure.
- Subject with endocrine abnormalities such as hyperprolactinaemia or thyroid dysfunction.
- Subject with malformation or absence of uterus.
- Subject tested positive for Human Immunodeficiency Virus (HIV) or Hepatitis B (by local laboratory; results obtained within 1 year prior to signing ICF are considered valid).
- Subject with contraindication or allergy/hypersensitivity to hCG, estrogen and progesterone.
Where it is running
- The Center for Human Reproduction — Manhasset, New York, United States
Full record on ClinicalTrials.gov
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