Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy

Completed · Phase 2

Conditions studied: Chronic Patellar Tendinopathy, Chronic PT

In brief

The goal of this study is to find an effective treatment for chronic patellar tendinopathy (PT). Investigators will conduct a 32-week randomized controlled clinical trial to determine whether platelet rich plasma (PRP) injections improve disease-specific clinical outcomes with correlation to a new method of ultrasound (US) imaging assessment called Acoustoelastography (AE). Positive findings of PRP compared to control would suggest future larger scale studies to help establish an optimal protocol for the nonsurgical management of PT.

Key facts

Study ID

NCT01843504

Run by

University of Wisconsin, Madison

People needed

29

Starts

2014-02-25

Expected to finish

2024-02-29

Last updated by the study team

2026-07-22

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age18-65
• chronic (>3months) patellar tendon pain;
• clinical exam findings consistent with PT;
• self-reported failure of supervised physical therapy;
• self-reported failure of at least 2 of the most common treatments (NSAIDs, relative rest, ice, bracing) for patellar tendinopathy.

You may not qualify if…

• inability to comply with follow-up requirements of study,
• history of bleeding disorders, low-platelet counts, other hematologic conditions;
• knee pain due to another possible etiology(e.g., degenerative joint disease);
• current or recent use of anticoagulation or immunosuppressive therapy;
• known allergy to acetaminophen or Lidocaine;
• self-reported pregnancy;
• worker's compensation injury;
• pending litigation;
• concurrent opioid use for pain

Where it is running

• Wisconsin Institute of Medical Research — Madison, Wisconsin, United States
• UW Sports Medicine Clinic at Research Park — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.