Phase Analysis and Obstructive CAD on Rubidium PET
Withdrawn before enrolling · Phase 2
Conditions studied: Coronary Artery Disease
In brief
Rubidium myocardial perfusion PET is an imaging test used to diagnose patients with abnormal blood flow to the heart secondary to narrowing of the heart vessels. Phase analysis is a computer method that is applied after the PET test is done. It is used to determine when a region of the heart contracts relative to other heart regions in the heart beating cycle. Initial data suggest that regions of the heart with abnormal blood flow change the pattern of contraction from rest to stress conditions. That is, regions of the heart with abnormal blood supply become dyssynchronous when compared to the normal regions of the heart. This study will investigate whether phase analysis may aid the visual interpretation of rubidium myocardial perfusion PET studies by determining the areas of the heart that are not beating in synchrony with the normal heart regions. This information will be used as a proxy for poor blood supply. The gold standard will be coronary angiography by which the percent narrowing of the heart vessels is assessed.
Key facts
- Study ID
- NCT01840696
- Run by
- Emory University
- People needed
- 0
- Starts
- 2013-10-01
- Expected to finish
- 2014-05-01
- Last updated by the study team
- 2014-06-02
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male or female patients
- referred for myocardial perfusion imaging for suspected obstructive CAD
- 18 years of age or older.
You may not qualify if…
- Contraindications to regadenoson radionuclide imaging including severe reactive airway disease, unstable crescendo angina, high grade AV block, caffeine within 24 hours
- Documented prior myocardial infarction
- Severe claustrophobia
- Patients who may be pregnant.
Where it is running
- Emory University Hospital — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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