Breast Cancer Proteomics and Molecular Heterogeneity
Recruiting now
Conditions studied: Primary Breast Cancer, Recurrent/Metastatic Breast Cancer
In brief
Primary objective: The primary objective is to define the proteomic and molecular characteristics of primary and recurrent/ metastatic breast tumours with special focus on the expression of S100 protein and the estrogen receptor (ER), progesterone receptor (PR) and epidermal growth factor receptor 2 (HER2) genes Secondary objective: * To expand our understanding of the complex molecular pathways dictating the progression of breast cancer and their response to different treatment regimes. * To relate proteomic findings to survival data * To identify potential serum markers of breast cancer progression
Key facts
- Study ID
- NCT01840293
- Run by
- Cancer Trials Ireland
- People needed
- 1780
- Starts
- 2013-02-01
- Expected to finish
- 2038-01-01
- Last updated by the study team
- 2025-12-19
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Patients diagnosed with primary breast cancer attending hospital for the resection of their tumour tissue
- Or
- Patients with suspected or confirmed recurrent or metastatic breast cancer (Patient has a history of a biopsy- or surgically- (i.e. pathologically) confirmed primary breast cancer) attending hospital for the resection/biopsy and/or treatment of tumour tissue
- Or
- Patient with suspected (but not necessarily biopsy confirmed) newly diagnosed stage 4 breast cancer attending hospital for the resection/biopsy and/or treatment of their tumour tissue
- Patients receiving neoadjuvant treatment are also eligible (if applicable)
- Patients have to be ≥ 18 years of age
- Patients must be able to give informed consent
Where it is running
- Cork University Hospital — Cork, Ireland (enrolling)
- Beaumont Hospital — Dublin, Ireland (enrolling)
- St. Vincent's University Hospital — Dublin, Ireland (enrolling)
- University Hospital Waterford — Waterford, Ireland (enrolling)
- St James's Hospital — Dublin, Ireland
- University Hospital Limerick — Limerick, Ireland
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.