Safety Study of Post Tonsillectomy Ibuprofen Use in Adults

Status unconfirmed · Not applicable

Conditions studied: Secondary Post Tonsillectomy Hemorrhage, Primary Post Tonsillectomy Hemorrhage

In brief

The purpose of this study is to determine if ibuprofen use after electrocautery tonsillectomy increases the post-tonsillectomy hemorrhage rate. Hypothesis: Use of ibuprofen does not increase the post-tonsillectomy hemorrhage rate. Primary outcome: Rate of tonsillar hemorrhage following adult tonsillectomy in those receiving narcotic pain medications plus ibuprofen compared to those receiving narcotics alone. Secondary outcome: Determine whether ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), decreases post tonsillectomy pain, narcotic pain medication use, or cost of pain management.

Key facts

Study ID

NCT01837810

Run by

Brooke Army Medical Center

People needed

810

Starts

2013-04-01

Expected to finish

2016-05-01

Last updated by the study team

2013-04-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults 18 years old or older
• Scheduled for tonsillectomy

You may not qualify if…

• Prisoners
• Pregnancy
• Allergy to ibuprofen
• History of vasculopathy to include Lupus or Wegener's or Disseminated Intravascular Coagulation (DIC)
• Any other bleeding disorder to include Von Willebrand Disease and others
• Active Neoplasm of any kind
• Tonsillectomy in combination with any sleep surgical procedure or palatal procedure

Where it is running

• Brooke Army Medical Center — Fort Sam Houston, Texas, United States (enrolling)
• Wilford Hall Ambulatory Surgical Center — Lackland Air Force Base, Texas, United States
• Madigan Army Medical Center — Tacoma, Washington, United States

Full record on ClinicalTrials.gov

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