Dismantling Mindfulness: Contributions of Attention vs. Acceptance

Completed · Not applicable

Conditions studied: Mild-moderate Unipolar Depression; Persistent Negative Affect

In brief

This study addresses NCCAM's request for research that investigates the neuropsychological mechanisms underlying mind-body therapies, and for precise criteria and better delineation of meditation practices. The purpose of this study is to assess the clinical efficacy and mechanism of action of 2 component practices of "mindfulness meditation", i.e. focused awareness (FA) and open monitoring (OM) in comparison to each other and to the standard package, Mindfulness-Based Cognitive Therapy (MBCT).

Key facts

Study ID

NCT01831362

Run by

Brown University

People needed

104

Starts

2013-02-01

Expected to finish

2016-03-15

Last updated by the study team

2018-11-05

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English-speaking
• ages 18-65
• mild-severe levels of depression or high level of negative affect

You may not qualify if…

• Current:
• age <18 or >65
• inability to read and write in English
• Extremely severe levels of depression
• active suicidal ideation
• presence of Axis I personality disorder
• panic disorder
• post-traumatic stress disorder
• obsessive-compulsive disorder
• eating disorder, or substance abuse/dependence
• current psychotherapy
• change in antidepressant medication type or dosage in the last 8 weeks.
• Lifetime history exclusions:
• bipolar disorder
• psychotic disorders
• persistent antisocial behavior or repeated self-harm,
• borderline personality disorder,
• organic brain damage
• regular meditation practice

Where it is running

• Brown University Clinical and Affective Neuroscience Laboratory — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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