The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery

Completed · Not applicable

Conditions studied: Diabetes, Hyperglycemia, Surgical Site Infection

In brief

The purpose of this study was to investigate the effects of three different glycemic treatment conditions (tight, conventional, and standard) in the intraoperative period on: 1) postoperative surgical site infections, and 2) postoperative procalcitonin, and C-reactive protein levels in patients undergoing open-heart surgery. Secondary aims of the study were to investigate the effects of the three glycemic treatment conditions on: 1) intraoperative blood glucose; 2) intraoperative glycemic stability; and 3) intensive care unit length of stay, in patients undergoing open-heart surgery.

Key facts

Study ID

NCT01831154

Run by

James A. Haley Veterans Administration Hospital

People needed

37

Starts

2010-05-01

Expected to finish

2011-10-01

Last updated by the study team

2017-04-24

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• over the age of 21
• on cardiopulmonary bypass or off cardiopulmonary
• elective or urgent coronary artery bypass graft (CABG) surgery
• CABG with or without combined valve surgery
• valve surgery

You may not qualify if…

• chronically immunosuppressed
• suffered from end-stage organ disease
• currently had active infections
• underwent emergent or salvage CABG surgery
• had an implanted insulin pump
• were in another interventional clinical trial.

Where it is running

• James A. Haley VAH — Tampa, Florida, United States

Full record on ClinicalTrials.gov

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