Rilonacept (Arcalyst ®) in the Treatment of Subacromial Bursitis
Completed · Not applicable
Conditions studied: Subacromial Bursitis
In brief
To date no trials have been performed looking at whether or not intra-bursal injection of an IL-1 antagonist provides pain relief similar to that of a corticosteroid injection. The subcutaneous injection of anakinra, an IL-1 receptor antagonist, in patients with shoulder pain due to rotator cuff tendonitis and subacromial bursitis was efficacious in relieving pain but this information was presented as a case series in a letter to the editor format, so the validity of these results would require additional testing \[Omoigui S, et al. 2004\]. Based mainly on the data from the intra-articular administration of anakinra, there have not been any adverse trends in outcomes or safety to suggest that intra-bursal injection of rilonacept will carry an increase risk of adverse events. The purpose of this trial is to compare the improvement in pain and function of patients with clinical symptoms and signs of subacromial bursitis of rilonacept vs. corticosteroid injection (standard of care).
Key facts
- Study ID
- NCT01830699
- Run by
- Keesler Air Force Base Medical Center
- People needed
- 33
- Starts
- 2013-03-01
- Expected to finish
- 2014-03-01
- Last updated by the study team
- 2014-08-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- At least 18 years of age or older and at a minimum have a recent history (more than 3 days worth) of shoulder pain with moderate to severe tenderness to palpation over the subacromial bursa.
You may not qualify if…
- Allergies to lidocaine, marcaine, or kenalog.
- Allergies to rilonacept
- Flare of active inflammatory arthritis (such as a flare of Rheumatoid Arthritis)
- Gout or Pseudogout attack of the shoulder with subacromial tenderness
- Active infection
- Actively receiving chemotherapy, radiation therapy, or anticipating surgery for neoplasia
- Active myocardial infarction
- Clinical and/or radiographic evidence of a fracture (clavicular, humeral, or other).
Where it is running
- Keesler Medical Center — Keesler Air Force Base, Mississippi, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.