Bulimia Nervosa: A Biobehavioral Study (The Eating Disorder Study)

Completed

Conditions studied: Bulimia Nervosa

In brief

The purpose of this study is to examine biological (e.g., energy expenditure, neuroendocrine and appetitive hormones)and behavioral (e.g., binge eating and purging) correlates of weight suppression and current dieting status in women with bulimia nervosa. The investigators have differentiated between a diet-induced long-term energy imbalance (weight suppression, or the difference between one's highest-ever body weight and current weight) and a short-term energy imbalance (current dieting to either lose weight or avoid weight gain). This study will elucidate how two common yet largely unexplored types of dieting influence biological and behavioral variables in patients with bulimia nervosa, which could lead to modifications of prevailing models of bulimia nervosa and new strategies for improving treatment outcome.

Key facts

Study ID

NCT01830374

Run by

Drexel University

People needed

132

Starts

2012-08-01

Expected to finish

2018-05-31

Last updated by the study team

2018-07-30

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of bulimia nervosa according to the proposed DSM-V criteria
• Either currently receiving eating disorder treatment or actively seeking treatment
• BMI above 18.5 and below 30
• Not experiencing any signs of menopause
• Medically stable as determined by each site's study physician

You may not qualify if…

• Change in pharmacological treatment over past 4 weeks
• Currently taking atypical antipsychotic medications
• History of anorexia nervosa within the past year
• Pregnancy
• Currently taking medications that could alter hormone levels or metabolism
• Disorders affecting metabolism or hormone levels
• Non-removal metallic object
• Co-occurring severe mental illness
• At risk for suicide

Where it is running

• Columbia University — New York, New York, United States
• Drexel University — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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