Effects of Simple Sodium Alignment on Clinical Outcomes

Completed

Conditions studied: Complication of Hemodialysis

In brief

A difference between dialysate and serum sodium concentration leads to diffusive sodium transfer across the dialyzer membrane. The consequences of diffusive sodium flux into the patient can be chronic sodium overload leading to overhydration, hypertension, cardiovascular disease, and other problems. Diffusive sodium flux out of the patient can lead to intradialytic blood pressure instability. A simple strategy for alignment of dialysate and serum sodium concentrations was implemented starting in April/May 2010 in order to minimize the problems particularly associated with chronic sodium overload.

Key facts

Study ID

NCT01825590

Run by

Renal Research Institute

People needed

148

Starts

2011-05-01

Expected to finish

2014-08-01

Last updated by the study team

2016-02-24

Who can join

Age: 18 and older, up to 88. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects on hemodialysis

You may not qualify if…

• None

Where it is running

• Renal Research Institute — New York, New York, United States

Full record on ClinicalTrials.gov

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