The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO)

Completed

Conditions studied: Secondary Malignant Neoplasm of Vertebral Column

In brief

The main purpose of this study is to utilize a comprehensive, prospective clinical database to collect patient, diagnostic and treatment variables along with disease specific and generic health related quality of life (HRQOL) data on consecutively treated patients with metastatic spine tumors. The objectives are to determine the validity and reliability of the Spine Cancer Outcomes Questionnaire (SCOQ) for use in the assessment of spine tumor outcomes, to determine if the Spine Instability Neoplastic Score (SINS) Classification is a valid tool for predicting the stability of spine in metastatic spine disease, and to determine the efficacy of surgery versus radiotherapy for the treatment of impending instability secondary to metastatic disease of the spine.

Key facts

Study ID

NCT01825161

Run by

AO Foundation, AO Spine

People needed

454

Starts

2013-08-01

Expected to finish

2019-12-01

Last updated by the study team

2022-09-13

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Signed informed consent
• Age between 18 and 75 years
• Able to read and write English at an elementary level
• Diagnosis of metastatic tumor of the spine

You may not qualify if…

• The primary cancer site is central nervous system or spine
• History of substance abuse (recreational drugs, alcohol) within 12 months prior to screening
• Is a prisoner
• A disease or condition that would, in opinion of the investigator, preclude accurate evaluation (e.g. significant psychiatric disease)

Where it is running

• Kansas University Medical Center — Kansas City, Kansas, United States
• Johns Hopkins University — Baltimore, Maryland, United States
• Mayo Clinic — Rochester, Minnesota, United States
• Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
• MD Anderson Cancer Center — Houston, Texas, United States
• Vancouver General Hospital — Vancouver, British Columbia, Canada
• Sunnybrook Health Sciences Center — Toronto, Ontario, Canada
• University of Toronto Hospital — Toronto, Ontario, Canada
• Montreal General Hospital — Montreal, Quebec, Canada
• National Center for Spinal Disorders — Budapest, Hungary

Full record on ClinicalTrials.gov

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