Dietary Fat, Eicosanoids and Breast Cancer Risk

Completed · Not applicable

Conditions studied: Breast Cancer

In brief

The primary objective of this investigation is to determine whether diets designed to increase plasma n3 concentrations (a low fat diet, with or without n3 fatty acid enrichment), will favorably affect sex hormone distribution in women in a direction associated with reduced risk of sex hormone-mediated cancer development. Specifically, we hypothesize that an increased concentration of circulating n3 fatty acids will reduce the biochemical markers associated with increased risk for developing certain sex hormone mediated cancers such as breast cancer

Key facts

Study ID

NCT01824498

Run by

USDA Grand Forks Human Nutrition Research Center

People needed

18

Starts

2004-01-01

Expected to finish

2010-11-01

Last updated by the study team

2018-08-31

Who can join

Age: 40 and older, up to 70. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Postmenopausal women
• 45 to 70 years old,
• at least one year since their last menstrual period
• not using hormone replacement therapy,
• BMI between 19 -29
• willingness to discontinue use of over-the-counter medications with anti-prostaglandin activity such as aspirin or non-steroidal anti-inflammatory medications
• consumption of a "Typical " American diet with no unusual dietary practices such as compliance with a strict vegetarian diet
• willingness to comply with the demands of the experimental protocol.

You may not qualify if…

• Smoking
• Known disease process, and 3) Use of prescription medications, including hormone replacement therapy.

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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