Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression?

Completed · Not applicable

Conditions studied: Major Depressive Disorder, Mood Disorders

In brief

The goal of this project is to determine whether genetic information can be used to predict response to an internet-based treatment of depression. Several studies now indicate that completing an internet-based treatment for depression, called Deprexis, can significantly improve symptoms of depression. However, not everyone improves. The purpose of this study is to determine whether genetic profile can predict who is likely to improve.

Key facts

Study ID

NCT01818453

Run by

University of Texas at Austin

People needed

500

Starts

2013-03-01

Expected to finish

2015-11-01

Last updated by the study team

2015-11-09

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English-speaking
• Have reliable access to the internet (i.e., dialup or broadband access)
• Be willing to donate saliva for DNA research
• Have a current symptoms of depression
• Be stable on medication and/or therapy (i.e. no changes within 2 weeks of study entry)

You may not qualify if…

• Any diagnosis of a psychotic or bipolar disorder
• Meeting for alcohol/drug dependence in the past year
• Having current suicidal risk warranting crisis intervention

Where it is running

• The University of Texas at Austin — Austin, Texas, United States

Full record on ClinicalTrials.gov

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