Uridine Adolescent Bipolar Depression Randomized Controlled Trial

Completed · Not applicable · Has a placebo group

Conditions studied: Bipolar Disorder, Bipolar Depression, Manic Depression

In brief

This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for depressed adolescents with bipolar disorder (i.e. "bipolar depression"). Participants initially randomized to placebo who complete the 6-week protocol will be offered 6 months of open-label uridine treatment and follow-up. Participants initially randomized to uridine will be offered the open-label treatment as well.

Key facts

Study ID

NCT01805440

Run by

University of Utah

People needed

62

Starts

2013-08-01

Expected to finish

2015-12-01

Last updated by the study team

2018-03-12

Who can join

Age: 13 and older, up to 21. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Participants must not meet DSM criteria for a primary psychotic disorder, a developmental disorder or substance use disorder.
• Participants must not be at high risk for suicidal or homicidal actions.
• Participants must not be pregnant or breastfeeding.
• Participants must not have a contraindication to magnetic resonance imaging (e.g. ferromagnetic implant, or claustrophobic anxiety).
• Incarcerated persons are excluded, because this study is not approved for Research Involving Prisoners.

Where it is running

• University of Utah — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.