Reducing CVD Risk in Caregivers: A Brief Behavioral Activation Intervention
Completed · Not applicable
Conditions studied: Depressive Symptoms, Inflammation
In brief
Cardiovascular disease and depression are some of the most costly illnesses to society, and caring for a loved-one with Alzheimer's disease has been associated with increased risk for both depression and cardiovascular disease. Indeed, depressive symptoms have been linked with elevated plasma concentrations of D-dimer and Interleukin-6 (IL-6), both of which are associated with increased risk for cardiovascular disease (CVD). The present research tests a brief behavioral intervention for reducing both depressive symptoms and CVD biomarkers in Alzheimer caregivers. We hypothesize that caregivers receiving a brief Behavioral Activation (BA) therapy will show greater reductions in depressive symptoms and in CVD biomarkers relative to those randomized to a time-equivalent Information and Support (IS) therapy.
Key facts
- Study ID
- NCT01802554
- Run by
- University of California, San Diego
- People needed
- 100
- Starts
- 2008-04-01
- Expected to finish
- 2013-02-01
- Last updated by the study team
- 2016-06-13
Who can join
Age: 55 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged 55 or older and providing at-home care for a care recipient (CR) with a physician-diagnosis of Alzheimer's disease (AD) or related dementia.
You may not qualify if…
- Receiving beta-blocking medications at enrollment
- Receiving treatment with Anticoagulant medications
- Severe hypertension (>200/120 mmHg)
- Diagnosed with a terminal illness with a life expectancy <6 months
- Enrolled in another intervention study
Where it is running
- University of California San Diego — La Jolla, California, United States
Full record on ClinicalTrials.gov
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