Type 2 Diabetes and Exercise Function in Single Leg Exercises
Completed · Not applicable
Conditions studied: Type 2 Diabetes
In brief
This study plans to learn more about the effects of type 2 diabetes (T2DM) on exercise blood flow and muscle oxygen uptake. This study will evaluate \& compare exercise function during single leg plantar flexion exercise in a total of 45 subjects from the Denver area (15 lean controls, 15 people with T2DM, and 15 overweight control subjects). Differences between the exercise responses in people with T2DM and healthy people will help further identify the disease process of T2DM and direct future research of treatments and interventions.
Key facts
- Study ID
- NCT01793909
- Run by
- University of Colorado, Denver
- People needed
- 55
- Starts
- 2012-06-01
- Expected to finish
- 2018-05-31
- Last updated by the study team
- 2023-07-12
Who can join
Age: 30 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Men and women with and without type 2 diabetes
- 30-70 years of age
- Lean and overweight
- Sedentary subjects not participating in a regular exercise program (<one bout of exercise/week)
You may not qualify if…
- Documented cardiovascular disease
- Uncontrolled hypertension: systolic blood pressure (SBP) > 150, diastolic blood pressure (DBP)> 110
- Obstructive pulmonary disease or asthma
- Peripheral neuropathy
- Subjects taking beta blockers, insulin, or Thiazolidinediones (TZD)
- Current or past smoking within the last 2 years
- Anemia
- Control HbA1c > 6, T2DM HbA1c > 10
- Type 1 diabetes
- Any implanted metal in subject's body
Where it is running
- University of Colorado Denver, Anschutz Medical Campus — Aurora, Colorado, United States
Full record on ClinicalTrials.gov
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