Treatment for Presumed Ocular Histoplasmosis
Status unconfirmed · Phase 1/Phase 2
Conditions studied: Ocular Histoplasmosis
In brief
The purpose of this study is to monitor safety outcomes for patients being treated with intravitreal aflibercept injections for choroidal neovascularization secondary to Presumed Ocular Histoplasmosis Syndrome.
Key facts
- Study ID
- NCT01790893
- Run by
- John Kitchens, MD
- People needed
- 40
- Starts
- 2013-03-01
- Expected to finish
- 2014-08-01
- Last updated by the study team
- 2014-06-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Active choroidal neovascularization (CNV) secondary to presumed ocular histoplasmosis demonstrated by active leakage on fluorescein angiography with spectal domain OCT evidence of subretinal or intraretinal fluid or PED.
- Active CNV may also be defined as demonstrating active subretinal hemorrhage.
- ETDRS Best corrected visual acuity 20/20-20/320.
- willing and able to comply with all study clinic visits and study related procedures.
- Willing to use and practice more than one form of contraceptives during the 13 month study for male and female.
- Provide signed informed consent
- Able to understand and complete study related questionnaires
You may not qualify if…
- Under 18 years of age
- CNV due to other causes than Presumed Ocular Histoplasmosis
- Previous treatment in the study eye within 6 months prior to Day 1
- More than 5 Intravitreal injections of anti-VEGF therapy within previous 12 months
- Any clinical evidence of any other ocular condition other than Ocular histoplasmosis
- History of allergy to fluorescein
- Pregnant( or planning on becoming pregnant within the next 13 months) or breast feeding women
- Sexually Active Men or Women who are NOT willing to practice more than one form of contraceptives during the next 13 months.
- Anticipated or previous (within previous 3 months) systemic anti-VEGF therapy
Where it is running
- Southeast Retina — Augusta, Georgia, United States (enrolling)
- Retina Associates of Kentucky — Lexington, Kentucky, United States (enrolling)
- Cincinnati Eye Institute — Cincinnati, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.