Walnuts and Glucose Variability
Stopped early · Not applicable
Conditions studied: Type-2 Diabetes
In brief
Persons with type 2 diabetes mellitus (T2DM) have swings in their blood sugar levels that may lead to a higher risk of developing heart disease. An important part of diabetes management involves eating a diet to prevent large swings in blood sugar levels. Walnuts contain fat, protein and fiber that may reduce the swings in blood sugar. The purpose of this study is to compare the effects of a walnut-free American Diabetes Association (ADA) diet versus 2 levels of walnut-enriched ADA diets on blood sugar swings. Eighteen male and female adults with T2DM will participate in the study. Subjects will be randomized to consume an ADA diet with or without walnuts for 3 consecutive days every other week. Subjects must test their blood sugar twice daily and wear a continuous glucose monitor during the three 72-hour study periods. Subjects will be between 40 and 70 years of age and will be recruited from the surrounding community using flyers and public service announcements. Consent will take place in the Department of Nutrition at Loma Linda University by the study investigators. In total, subject participation will last 5 weeks and all meals will be provided during the 3 study periods.
Key facts
- Study ID
- NCT01787214
- Run by
- Loma Linda University
- People needed
- 18
- Starts
- 2013-06-01
- Expected to finish
- 2013-09-01
- Last updated by the study team
- 2014-03-18
Who can join
Age: 40 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- adults between age 40 and 70 years with type 2 diabetes
- duration of type 2 diabetes more than 6 months but less than 10 years
- HbA1c 6.0-8.0%
- BMI 25-40 kg/m2
- diet controlled or stable dose of metformin for at least 3 months
- willing to test blood glucose with personal meter twice a day during study test days
You may not qualify if…
- using oral hypoglycemic agents or insulin
- history of ischemic heart disease or congestive heart failure
- history of severe diabetic complication (neuropathy, renal failure, stroke)
- taking medication affecting glucose levels (i.e. corticosteroids)
- active infectious disease
- active malignancy
- pregnant or breast feeding woman
- smoker
- history of daily caffeine or alcohol intake
- known allergy to nuts
- lactose or gluten intolerance
Where it is running
- Loma Linda University, Nichol Hall — Loma Linda, California, United States
Full record on ClinicalTrials.gov
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