The Effect of Aerobic Exercise on Cognitive Function and Sleep Quality in Individuals With Multiple Sclerosis
Completed · Not applicable
Conditions studied: Multiple Sclerosis
In brief
In addition to the typical motor and sensory impairments, individuals with multiple sclerosis (MS) often experience cognitive dysfunction and sleep disturbances. Cognitive impairment occurs in 40 % - 70% of patients with MS. In addition, sleep problems in individuals with MS are very common, and approximately 50% of patients with MS have a diagnosable sleep disorder. The research believes that aerobic exercise improve cognitive function and improve sleep quality.
Key facts
- Study ID
- NCT01783665
- Run by
- Catherine Siengsukon, PT, PhD
- People needed
- 28
- Starts
- 2012-08-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2019-08-28
Who can join
Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- diagnosis of relapsing remitting or secondary progressive MS
- score 3-7 on the EDSS
- score < 55 on the Symbol Digit Modalities Test
- score > 5 on the Pittsburgh Sleep Quality Index
You may not qualify if…
- history of alcohol/drug abuse or nervous system disorder other than MS
- severe physical, neurological, or sensory impairments that would interfere significantly with testing
- developmental history of learning disability or attention-deficit/hyperactivity disorder
- relapse and/or corticosteroid use within four weeks of assessment
- unable to give consent
- uncorrected vision loss that would interfere significantly with testing
- score less than 24 on MMSE
- Acute ischemic cardiovascular event or coronary artery bypass surgery less than 3 months ago
- Either unable to physically perform the exercise test using the recumbent stepper or demonstrate absolute indications for terminating exercise that follows the American College of Sports Medicine's (ACSM) guidelines
- Uncontrolled blood pressure with medication (BP > 190/110mmHg)
Where it is running
- University of Kansas Medical Center — Kansas City, Kansas, United States
Full record on ClinicalTrials.gov
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