Analgesia After Total Shoulder Arthroplasty

Completed · Phase 4

Conditions studied: Total Shoulder Arthroplasty

In brief

The purpose of this study is to determine which medication(s) should be included in the interscalene nerve block (an injection of local anesthetic \[numbing medicine\] near nerves in the shoulder) for patients undergoing total shoulder arthroplasty (shoulder replacement). The ideal nerve block would reduce pain after shoulder surgery without causing a great deal of muscle weakness.

Key facts

Study ID

NCT01782872

Run by

Hospital for Special Surgery, New York

People needed

80

Starts

2012-10-01

Expected to finish

2014-02-01

Last updated by the study team

2016-05-18

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with osteoarthritis
• Primary total shoulder arthroplasty
• Age 18 to 80 years old
• Planned use of general anesthesia
• Planned use of a brachial plexus nerve block for postoperative analgesia
• Ability to follow study protocol

You may not qualify if…

• Patients younger than 18 years old and older than 80
• Allergy or intolerance to one of the study medications
• Patients with an American Society of Anesthesiologists (ASA) physical status of IV
• Patients with insulin-dependent diabetes
• Patients with hepatic (liver) failure
• Patients with chronic renal (kidney) failure
• Bradycardia (heart rate < 50) or hypotension (systolic blood pressure < 90 mmHg)
• Chronic opioid use (taking opioids for longer than 3 months) (or active diagnosis of complex regional pain syndrome [CRPS]/reflex sympathetic dystrophy [RSD])
• Lack of English fluency

Where it is running

• Hospital for Special Surgery — New York, New York, United States

Full record on ClinicalTrials.gov

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