Hypercapnia: Cognitive Effects and Monitoring
Completed · Not applicable
Conditions studied: Hypercapnia, Exercise, Nitrogen Narcosis, Diving, Immersion
In brief
The investigators will simulate the conditions of a working, helmeted diver by using exercising, "head out" immersed subjects to test the following hypotheses: 1. An algorithm can be developed which predicts cognitive performance in immersed exercising divers, based on the exhaled carbon dioxide (PETCO2) and the diver's inspired partial pressures of oxygen and nitrogen (PIO2 and PIN2). 2. PETCO2 using mass spectrometry is an accurate estimate of arterial carbon dioxide (PaCO2) at rest and during immersed exercise and can be used as a PaCO2 surrogate at levels exceeding 50 mmHg and depths up to 158 fsw (gas density 6.4 g/l, similar to 165 fsw density of 6.8 g/l).
Key facts
- Study ID
- NCT01782625
- Run by
- Duke University
- People needed
- 58
- Starts
- 2013-01-01
- Expected to finish
- 2016-02-01
- Last updated by the study team
- 2016-05-25
Who can join
Age: 18 and older, up to 50. Sex: male. Healthy volunteers: accepted.
You may qualify if…
- healthy,
- male,
- age greater than 18,
- age less than 50
You may not qualify if…
- smoker,
- asthma,
- cardiac disease,
- inability to pedal a bicycle ergometer,
- inability to perform vigorous exercise
Where it is running
- Duke Center for Hyperbaric Medicine and Environmental Physiology — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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