Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

Stopped early · Phase 3

Conditions studied: Screening Colonoscopy

In brief

The purpose of this study is to determine which of the methods of colonoscopy viz. water insufflation or air insufflation or carbon dioxide insufflation is better in detecting the adenomas in colon and also which of these methods is best tolerated by patients. Hypothesis: the investigators hypothesize that in patients undergoing first time screening colonoscopy a higher Adenoma Detection Rate will be found in the proximal colon in the group randomized to the water method compared to those randomized to the air or CO2 insufflation methods

Key facts

Study ID

NCT01782014

Run by

Loma Linda University

People needed

450

Starts

2013-02-01

Expected to finish

2015-03-01

Last updated by the study team

2016-02-01

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Asymptomatic patients with average risk for colorectal cancer, who are scheduled for first-time screening colonoscopy, will be enrolled.

You may not qualify if…

• decline to be randomized
• unable to give consent
• non-screening (surveillance or diagnostic) colonoscopy
• current participation in other colonoscopy studies
• a medical condition that could increase the risk associated with colonoscopy
• pregnancy
• those with a known family history of polyposis syndromes or a family history of colon cancer

Where it is running

• Loma Linda University Medical Center — Loma Linda, California, United States

Full record on ClinicalTrials.gov

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