Weight Loss Study-Mechanism Underlying the Improvement of Insulin Resistance in Response to Weight Loss

Completed · Not applicable

Conditions studied: Obesity, Weight Loss

In brief

The main purpose of this study is to assess factors mediating the changes in insulin sensitivity and glucose tolerance before and after 10 lbs ± or 2% weight loss reduction as well as 2, 3, 6, 12, and 24 months after initiation of a low calorie diet. The investigators will also study the following: 1. The impact of diet induced weight loss on hormones/adipokine levels 2. The impact of diet induced weight loss on leptin tolerance

Key facts

Study ID
NCT01780870
Run by
Beth Israel Deaconess Medical Center
People needed
5
Starts
2012-09-01
Expected to finish
2017-01-01
Last updated by the study team
2017-08-07

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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