Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy

Completed · Not applicable

Conditions studied: Focal Epilepsy

In brief

This study will evaluate a type of Magnetic Resonance Imaging (MRI) sequence called arterial spin labeling (ASL). The investigators hope that ASL can better localize areas of the brain (lesions) that cause epilepsy. This type of MRI does not require contrast, does not use any radiation, and adds on 4 minutes to the routine MRI that is done for patients with epilepsy. The study hypothesis is that in patients with refractory epilepsy, Arterial Spin Labeling (ASL) MRI will show areas of abnormality in the brain to the same degree as single-photon emission computerized tomography (SPECT) and positron emission tomography (PET) studies.

Key facts

Study ID

NCT01772654

Run by

Mayo Clinic

People needed

73

Starts

2013-01-01

Expected to finish

2013-11-01

Last updated by the study team

2015-03-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Medically refractory partial epilepsy.
• Over the age of 18 years.
• Scheduled to have routine epilepsy-protocol MRI after initial evaluation in neurology clinic at Mayo Clinic, Rochester.
• Anticipated to undergo epilepsy monitoring unit (EMU) monitoring.

You may not qualify if…

• Patients with a generalized epilepsy.
• Under the age of 18 years.
• Unable to undergo MRI imaging of the brain.

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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