Impulsivity and Thought Process Disorder in Patients With Active Suicidal Ideation and Depression
Withdrawn before enrolling · Not applicable · Has a placebo group
Conditions studied: Impulsivity, Active Suicidal Ideation, Depression
In brief
This study is dedicated to achieving a better understanding of how the brain processes information. Specifically, the investigators are studying cognitive function, thought process, and impulsivity in people with and without suicidal thoughts. You are being asked to participate in a research study to learn how the use of a medication, risperidone, improves your symptoms of depression. Specifically the investigators are studying the effectiveness of reducing the thought of suicide and other symptoms of severe depression. Risperidone is approved by FDA for the treatment of schizophrenia and bipolar mania, and clinical practice suggests that it might benefit patients with major depressive disorder. During clinical trials with 2607 patients, risperidone was proved to be safe. This is a pilot study to test a new indication of risperidone for treatment of severe depression. The study medication will be given in addition to usual psychiatric care.
Key facts
- Study ID
- NCT01770600
- Run by
- University of Alabama at Birmingham
- People needed
- 0
- Starts
- 2010-04-01
- Last updated by the study team
- 2015-05-28
Who can join
Age: 19 and older, up to 64. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age : 19-64
- Suicidality score of > 4 on Montgomery-Asberg Depression Rating Scale (MADRS)
You may not qualify if…
- pregnant,
- medically unstable,
- history of schizophrenia,
- schizoaffective disorder,
- bipolar disorder,
- psychosis NOS,
- urine drug screen positive for cocaine,
- marijuana or amphetamines,
- withdrawal from opiates,
- benzodiazepines or alcohol,
- currently on antipsychotic drug therapy. Also excluded are those subjects who require the use of mood stabilizers or antipsychotics.
Where it is running
- University of Alabama Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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