Effect of Monosodium L-Glutamate (MSG) and Nucleic Acid (IMP) on Satiety and Food Intake

Completed · Not applicable · Has a placebo group

Conditions studied: Nutrition Intervention

In brief

The objective of this study is to confirm that Monosodium L-Glutamate (MSG) supplementation, both alone or in combination with Nucleic Acid (IMP), enhances satiety and decreases food intakes at the next meal in healthy female adults.

Key facts

Study ID

NCT01761045

Run by

Ajinomoto Co., Inc.

People needed

80

Starts

2010-07-01

Expected to finish

2011-01-01

Last updated by the study team

2013-02-11

Who can join

Age: 30 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Healthy Female, 30 to 45 yrs old
• Non-smoker
• Non-heavy Drinker
• BMI between 18.5 and 25.0 inclusive at the screening visit

You may not qualify if…

• History or presence of any serious and/or chronic medical or clinical disease, including renal disease, hepatic (biliary) disease, uncontrolled hypertension or uncontrolled thyroid disease, surgical conditions, cardiovascular disease other than mild hypertension or dyslipidemias, myocardial infarction, or other conditions that in the opinion of the investigator may increase the risk of participation or compromise/confound the study results
• History or diagnosis of type 1 or 2 diabetes mellitus or other uncontrolled endocrine disease
• Dysgeusia
• Any history of gastrointestinal disease or currently on treatment for a digestive disease
• Eating disorder or abnormal eating habits
• Undergone a recent significant weight change (gain or loss)
• Participating on a weight-loss program within the past 6 months prior to entry into the study
• Taking any medications for the alimentary system
• Allergy or sensitivity to foods or food additives
• History of using habitual drugs and/or alcohol abuse within the past year
• Psychosis and/or suffering from any other condition(s) which might render the individual unable to comply with the protocol or place subjects at increased risk at the discretion of the PI
• Used any investigational drug or product within the 1 month prior to the screening visit
• On special diet such as vegetarian
• Dislike the preloading soup and/or the provided lunch and/or study snacks
• Currently breast feeding and/or pregnant in the past 6 months

Where it is running

• IBERICA Clinical Research Center — Eatontown, New Jersey, United States

Full record on ClinicalTrials.gov

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