Testing Fish Oil Derivatives In Healing Of Chronic Venous Leg Ulcers

Completed · Not applicable · Has a placebo group

Conditions studied: Venous Stasis Ulcers

In brief

The purpose of this study is to test the efficacy of an oral, nutrient intervention containing the bioactive components of fish oil to promote healing of chronic venous leg ulcers (CVLU). If this systemic, nutrient intervention is found to alter the microenvironment of CVLU, the science of wound healing and care of patients with CVLU will be vastly improved.

Key facts

Study ID

NCT01754506

Run by

Ohio State University

People needed

41

Starts

2013-01-01

Expected to finish

2015-07-01

Last updated by the study team

2015-10-16

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• men and women
• ages 18-85 years
• having at least one existing CVLU between the ankle and knee for ≥ 3 months
• medical clearance to take 81mg/d of aspirin
• prescribed compression therapy; ambulatory
• ankle brachial pressure index (ABPI) of ≥ 0.8
• target wound of ≥ 1 x 1 inches (6.25 cm2)
• can understand English and sign own consent

You may not qualify if…

• allergy to fish or seafood
• exposed bone, tendon or fascia around target wound
• receiving warfarin or Plavix therapy
• immunologic related condition (e.g. Crohn's disease, systemic lupus erythematosus)
• chronic inflammatory skin diseases (e.g. pyoderma gangrenosum, psoriasis)
• requiring non-steroidal anti-inflammatory drugs > 2x a week
• nutritional supplements or corticosteroids
• chronic renal insufficiency
• already in a study related to CVLU.

Where it is running

• The Ohio State University College of Nursing — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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