Exosomal MicroRNA Expression in Children With Autism Spectrum Disorder

Completed

Conditions studied: Autism Spectrum Disorder

In brief

There is accumulating evidence that genetic expression plays a role in autism spectrum disorder, but the regulation of such genes is poorly understood. Small RNA particles, called microRNA (miRNA), have the ability to alter gene expression. These particles can be packaged and released from brain cells into the blood. Changes in miRNA may contribute to the patterns observed in autism spectrum disorder. The purpose of this study is to identify small RNA particles that regulate gene expression in autism spectrum disorder. The goal is to identify miRNA expression patterns which may improve our understanding and diagnosis of autism spectrum disorder.

Key facts

Study ID

NCT01749670

Run by

State University of New York - Upstate Medical University

People needed

45

Starts

2013-01-01

Expected to finish

2014-09-01

Last updated by the study team

2014-11-26

Who can join

Age: 4 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Children ages 4-17

You may not qualify if…

• neurological impairments (i.e. cerebral palsy, epilepsy)
• sensory deficits (i.e. sensory or visual impairments)
• psychological disorders (i.e. obsessive compulsive disorder, attention deficit disorder)
• control subjects with family history of autism spectrum disorder
• mental retardation
• history of preterm birth

Where it is running

• SUNY Upstate Medical University — Syracuse, New York, United States

Full record on ClinicalTrials.gov

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