Neutrophil Extracellular Trap Formation in Patients Undergoing Bone Marrow Transplant

Completed

Conditions studied: Bone Marrow Transplant

In brief

This is a prospective observational study to determine the point after bone marrow transplant in adults and children at which the neutrophils derived from the transplanted stem cells are competent to form functional neutrophil extracellular traps (NETs). Furthermore, given the importance of platelet function for NET formation, we also plan to examine platelet activation and function as well as the platelet transcriptome using the same clinical samples.

Key facts

Study ID

NCT01735565

Run by

University of Utah

People needed

23

Starts

2012-06-01

Expected to finish

2016-07-01

Last updated by the study team

2016-08-11

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Within one year of bone marrow transplant
• Informed consent

You may not qualify if…

• No specific exclusion criteria

Where it is running

• Huntsman Cancer Institute — Salt Lake City, Utah, United States
• Primary Children's Medical Center — Salt Lake City, Utah, United States
• University of Utah — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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