NAS Treatment - Opiate Versus Non-Opiate

Completed · Phase 4

Conditions studied: Neonatal Abstinence Syndrome

In brief

The purpose of this study is to compare two different medicines to treat babies with opiate withdrawal. The treatment medicines are morphine, which is an opiate, and clonidine, a non-opiate. Morphine is a narcotic medicine, with is included in most pain killers. Clonidine is another drug, but is different from morphine. It is also used for babies, and even adults for withdrawal symptoms. Both drugs are effective, but the purpose of this study is to see if one may be better than the other.

Key facts

Study ID

NCT01734551

Run by

Henrietta Bada

People needed

31

Starts

2011-09-01

Expected to finish

2014-12-01

Last updated by the study team

2017-09-12

Who can join

Age: 0 and older, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Admitted to Neonatal Intensive Care Unit (NICU)- Gestational age (GA) >or= 35 wks
• Known prenatal opiate exposure (maternal history, positive opiate screen, positive neonatal urine or meconium screen)
• Symptomatic with Finnegan Neonatal Abstinence Scores meeting NICU protocol for treatment

You may not qualify if…

• Seizures
• Major congenital malformations
• Unlikely to survive
• Parents not able to understand English

Where it is running

• University of Kentucky Medical Center — Lexington, Kentucky, United States

Full record on ClinicalTrials.gov

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