Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Completed · Phase 4 · Has a placebo group
Conditions studied: Postoperative Nausea and Vomiting
In brief
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic. The investigators will then compare the incidence of nausea and vomiting and the use of rescue anti-nausea medications in both groups. Our hypothesis is that patients receiving dexamethasone prior to duramorph containing spinal anesthesia for cesarean section will have a significantly lower incidence and severity of PONV at 0, 1, 3, 6, and 24 hours following surgery.
Key facts
- Study ID
- NCT01734161
- Run by
- Weill Medical College of Cornell University
- People needed
- 122
- Starts
- 2012-11-01
- Expected to finish
- 2015-08-01
- Last updated by the study team
- 2019-10-15
Who can join
Age: 18 and older, up to 46. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Women aged 18-46 presenting for scheduled primary or repeat cesarean sections and have consented to study
You may not qualify if…
- allergy to dexamethasone or morphine
- history of gastrointestinal disease
- history of severe nausea during pregnancy (hyperemesis gravidarum)
- use of anti-emetic in the past 24 hours
- history of gestational diabetes or diabetes mellitus
- history of hypertension prior to or during pregnancy
- presence of non-viable fetus
Where it is running
- Weill Cornell Medical College — New York, New York, United States
Full record on ClinicalTrials.gov
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