The Learning and Memory of the Experience of Pain

Completed · Not applicable

Conditions studied: Pain

In brief

This study investigates the learning and memory of pain.

Key facts

Study ID

NCT01731314

Run by

Massachusetts General Hospital

People needed

60

Starts

2013-01-01

Expected to finish

2018-01-01

Last updated by the study team

2019-08-13

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male and female healthy volunteers.
• 18-65 years of age.
• Right-handed.
• Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

You may not qualify if…

• Any previous experience with conditioned analgesia/hyperalgesia paradigms.
• Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
• Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
• Instability of responses to experimental heat pain
• Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
• Peripheral neuropathy.

Where it is running

• MGH East Campus, 149 13th St. — Charlestown, Massachusetts, United States

Full record on ClinicalTrials.gov

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