Impact of Black Pepper on Energy Expenditure and Substrate Utilization

Completed · Not applicable

Conditions studied: Obesity

In brief

As obesity rates worldwide continue to increase, there is a focus on identifying active food ingredients which increase metabolic rate which can be used as a dietary supplement in the treatment of overweight and obesity. Promising animal and cell studies have suggested a role for black pepper and an active component of black pepper, piperine, in energy expenditure. However, the effects of black pepper have not been determined in humans. The investigators hypothesis if that consumption of 1.5g black pepper (0.5g in each of three meals over one day) will result in an elevation in 24-h resting energy expenditure when contrasted to a control day (no black pepper, same diet intake).

Key facts

Study ID

NCT01729143

Run by

University of North Carolina, Chapel Hill

People needed

18

Starts

2011-04-01

Expected to finish

2011-07-01

Last updated by the study team

2016-04-06

Who can join

Age: 50 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Woman
• Postmenopausal
• Aged 50-65 years
• BMI 25-35kg/m2
• Not taking blood pressure or anti-inflammatory medications or any other medications that may impact the results
• Thyroid hormone profile within the normal reference range
• No medical condition which may impact the results (e.g. diabetes)
• Accustomed to eating regular meals including breakfast

You may not qualify if…

• Smoker
• Heavy exerciser (defined as >150 minutes/week for more than 3 months)
• Abuses alcohol or drugs
• Vegetarian

Where it is running

• UNC Chapel Hill Nutrition Research Institute — Kannapolis, North Carolina, United States

Full record on ClinicalTrials.gov

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