Treatment of Post-Traumatic Brain Injury (Post-TBI) Fatigue With Light Therapy

Completed · Not applicable

Conditions studied: Traumatic Brain Injury, Fatigue

In brief

This study aims to evaluate the efficacy of 4 weeks of daily light exposure in reducing Post-Traumatic Brain Injury (TBI) Fatigue immediately post-treatment and at a one-month follow up. The investigators hypothesize that individuals receiving 4 weeks of bright white light treatment will report significant reductions in fatigue compared to individuals receiving dim red light treatment for the same duration of time, and that these treatment effects will be maintained one month after treatment completion.

Key facts

Study ID: NCT01725750
Run by: Icahn School of Medicine at Mount Sinai
People needed: 88
Starts: 2012-11-01
Expected to finish: 2017-06-01
Last updated by the study team: 2019-08-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Documented TBI of any severity
At least 6 months post injury
Presence of clinically significant fatigue, operationalized as a score of 22 or more on the Multidimensional Assessment of Fatigue
Age 18 or older
English speaking

You may not qualify if…

Neurological disease other than TBI
Pregnancy (because of pregnancy fatigue)
Medical illness causing fatigue, such as anemia, hypothyroidism, HIV, renal failure, cirrhosis or cancer treatment in the past year
Current major depressive episode or substance abuse
Diagnosed sleep disorder or high risk for sleep apnea
History of bipolar disorder or manic or hypomanic episodes
Current chronic, severe headaches
Sensitivity to bright light
History of retinal damage or disease

Where it is running

The Brain Injury Research Center at Icahn School of Medicine at Mount Sinai — New York, New York, United States

Full record on ClinicalTrials.gov

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