Does First Oral Intake After Emergence Predict the Incidence of Post-operative Vomiting in Children?
Completed · Not applicable
Conditions studied: Post-operative Vomiting
In brief
Second only to pain, nausea and vomiting are the most uncomfortable complications of surgery and anesthesia. Unfortunately, our best defense against post-operative nausea and vomiting, a medicine called ondansetron (Zofran), is in dire national shortage. Consequently, non-pharmacological methods of prevention and treatment for post-operative nausea and vomiting have increased import. Following emergence from general anesthesia, children often request food and drink. There have been no studies to date that definitively determine the optimal first food or drink choice for these children. This study proposes to randomize children to either water or juice first intake following surgery. The investigators expect to find that children who consume glucose are less likely to vomit than those who first receive water.
Key facts
- Study ID
- NCT01725399
- Run by
- University of North Carolina, Chapel Hill
- People needed
- 183
- Starts
- 2012-10-01
- Expected to finish
- 2013-12-01
- Last updated by the study team
- 2014-08-07
Who can join
Age: 2 and older, up to 18. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Dental surgery
- Tonsillectomy and adenoidectomy
- Strabismus surgery
- Age 2-18
You may not qualify if…
- Patient refusal
- Parent refusal
- Allergy / contraindication to ondansetron
- Prone to vomiting
- Inpatient
- Preoperative anxiolysis with ketamine
- Recovery location other than PACU
- Nil per os at baseline
- Presence of enteric tube
- Contraindication to any part of the study protocol
Where it is running
- UNC Chapel Hill — Chapel Hill, North Carolina, United States
Full record on ClinicalTrials.gov
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