Nutritional Prevention of Exertional Muscle Dysfunction

Completed · Not applicable · Has a placebo group

Conditions studied: Muscle Dysfunction, Exertional Rhabdomyolysis, Muscle Strength

In brief

The investigators want to find out whether a choline supplement can protect muscle health in young men with very common genetic vulnerabilities. Men, who respond to a brief, but intense set of arm exercise and have a common genetic profile, will be asked to use a choline supplement for three weeks and a placebo for three weeks. Before the begin of the supplementation study and after 3 and 6 weeks the investigators will test response to the exercise challenge and ask that all consumed foods are recorded.

Key facts

Study ID

NCT01722448

Run by

University of North Carolina, Chapel Hill

People needed

68

Starts

2012-11-01

Expected to finish

2015-08-01

Last updated by the study team

2017-10-16

Who can join

Age: 18 and older, up to 45. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Caucasian
• choline intake less than 450 mg
• exertional muscle dysfunction
• susceptible genetic profile

You may not qualify if…

• severe chronic illness
• limited range of arm motion
• required use of prescription medication
• required use of dietary supplements

Where it is running

• UNC Nutrition Research Institute — Kannapolis, North Carolina, United States

Full record on ClinicalTrials.gov

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