Effects of Dexmedetomidine on Activity in the Subthalamic Nucleus

Completed · Phase 4

Conditions studied: Parkinson's Disease, Deep Brain Stimulation Surgery

In brief

The purpose of this research study is to find out whether dexmedetomidine changes brain cell activity in the subthalamic nucleus (STN).

Key facts

Study ID

NCT01721460

Run by

University of Wisconsin, Madison

People needed

6

Starts

2012-11-01

Expected to finish

2015-06-01

Last updated by the study team

2017-12-08

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled to undergo bilateral STN electrode implantation surgery with Micro-electrode recording for the treatment of Parkinson's disease.

You may not qualify if…

• Hypersensitivity to dexmedetomidine
• Bradycardia: Sinus rhythm slower than 50 bpm
• Known or suspected obstructive sleep apnea
• Suspected difficult intubation
• Pregnancy
• Under 18 years of age or over 85 years of age
• Cognitive disability impairing understanding the experiment or signing the informed consent form

Where it is running

• University of Wisconsin - Madison, School of Medicine and Public Health — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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