Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)

Stopped early · Not applicable

Conditions studied: Polycystic Ovary Syndrome, Infertility

In brief

Progestin-induced endometrial shedding (PIES) followed by clomiphene citrate is fertility treatment of choice in anovulatory women with polycystic ovary syndrome (PCOS). However, some preliminary data suggest that skipping PIES could result in a higher live birth rate. The investigators are performing the first randomized controlled trial to find out if skipping the use of progestin during fertility treatment of anovulatory PCOS women is associated with improved pregnancy and live birth rates compared to the traditional approach of using progestin prior to use of clomiphene citrate.

Key facts

Study ID
NCT01718444
Run by
University of Illinois at Chicago
People needed
27
Starts
2015-03-01
Expected to finish
2016-06-01
Last updated by the study team
2020-09-29

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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