Evaluation of Coagulation in Multiple Sclerosis

Completed

Conditions studied: Multiple Sclerosis

In brief

Recent research in multiple sclerosis (MS) have suggested that altered coagulation and vascular inflammation may play a role in pathophysiology of MS. Sonoclot is viscoelastic method of analyzing clot formation. This instrument will be used to compare coagulation in individuals with MS to healthy controls. A 24-hour dietary recall and food frequency questionnaire will help determine whether coagulation is modified by fish consumption.

Key facts

Study ID

NCT01711255

Run by

Bastyr University

People needed

69

Starts

2012-10-01

Expected to finish

2016-05-01

Last updated by the study team

2017-07-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnosis of clinically probable of clinically definite multiple sclerosis made by board certified neurologist. Subject must be willing to release medical information regarding diagnosis
• Controls must consider themselves healthy and be free of any neurological, autoimmune, endocrine or other chronic disease. Must also be free of any recent acute illness/injury that can influence inflammatory activity.
• Individuals must be 18 or older

You may not qualify if…

• Diagnosis of coagulation defect
• Use of anticoagulants (eg. warfarin, coumadin) or Aspirin within 30 days of entry.
• NSAID within 7 days of entry (dietary intake of fish oil or tumeric is acceptable)
• Pregnancy

Where it is running

• Bastyr University Clinical Research Center — Kenmore, Washington, United States

Full record on ClinicalTrials.gov

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