Neurofibromatosis Type 1 Brain Tumor Genetic Risk

Completed

Conditions studied: Neurofibromatosis Type 1, Pediatric Brain Tumor

In brief

This study will analyze DNA samples to determine associations between maternal and offspring genetic factors and pediatric brain tumor development in children with Neurofibromatosis Type 1. Participating families (mother, father, child) will be asked to complete a short questionnaire and provide DNA samples (either saliva or blood). The information gained from your participation may one day help doctors develop strategies to reduce brain tumor risk in individuals with NF1. Please note: there is no therapy associated with this study.

Key facts

Study ID

NCT01707836

Run by

Washington University School of Medicine

People needed

176

Starts

2012-10-01

Expected to finish

2017-05-08

Last updated by the study team

2017-05-09

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pediatric participant (born during 1994-2012) with NF1 and diagnosed with a brain tumor
• Biological mother or father (or full sibling if mother or father is unable to participate) able to participate
• All family members (pediatric participant, biological mother, and biological father or full sibling) must be willing to contribute a blood or saliva sample
• ability to understand consent forms

You may not qualify if…

• those who do not meet inclusion criteria

Where it is running

• Washington University — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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