Cognitive Behavioral Therapy for Paranoia in Schizophrenia

Completed · Not applicable

Conditions studied: Paranoid Delusions

In brief

The main objective of this study is to determine the preliminary efficacy of Paranoia-Focused Cognitive Behavioral Therapy (PFCBT) relative to standard care in the treatment of persecutory delusions in patients diagnosed with schizophrenia or schizoaffective Disorder.

Key facts

Study ID

NCT01704833

Run by

Weill Medical College of Cornell University

People needed

24

Starts

2006-09-01

Expected to finish

2017-06-01

Last updated by the study team

2018-12-04

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 to 65 years
• Met DSM IV diagnostic criteria for schizophrenia or schizoaffective disorder, confirmed by the Clinical Structural Diagnostic Interview (SCID, First et al, 1997) -Reported persistent and distressing paranoid delusion(s);
• A minimum severity score of 4 point Persecution subscale on The Positive and Negative Syndrome Scale (PANSS)
• Had an adequate trial (6 months or more) and were stabilized on antipsychotic medications (no change in psychiatric medication prescribed in the last month

You may not qualify if…

• Substance misuse or medical disorder identified as the primary cause of delusions

Where it is running

• Weill Cornell Medical College — New York, New York, United States

Full record on ClinicalTrials.gov

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