Feasibility and Diagnostic Accuracy of Myocardial Perfusion Imaging Using Early Imaging Protocol

Withdrawn before enrolling · Phase 4

Conditions studied: Coronary Artery Disease

In brief

The current protocol for myocardial perfusion imaging (MPI) entails imaging within 30-45 minutes after radiotracer injection, for both rest and stress studies. We hypothesize that early imaging 10 minutes after radiotracer injection provides high image quality and diagnostic accuracy comparable to 30-45 minutes MPI.

Key facts

Study ID

NCT01700972

Run by

St. Louis University

People needed

0

Starts

2013-02-01

Expected to finish

2014-08-01

Last updated by the study team

2014-03-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Men and women ≥18 years of age of any race /ethnicity
• Patient has undergone or is being scheduled for a clinically indicated cardiac catheterization with or without angioplasty
• Patient may have suffered myocardial infarction more than 3 days before MPI
• Patient may have undergone percutaneous transluminal coronary angioplasty (PTCA) or coronary stent placement more than 3 days prior to MPI
• Interval between T99m-MPI and cardiac catheterization is within 30 days
• Females are not pregnant and lactating
• Provide signed Informed Consent prior to undergoing the study procedures

You may not qualify if…

• Patients less than 18 years of age
• Female patient is pregnant or nursing
• Patient has been involved in any other investigative, radioactive research procedure within 7 days and during the study participation period
• History of 2nd or 3rd degree AV-block, or sinus node dysfunction unless the patients have a functioning artificial pacemaker
• Myocardial infarction within 3 days before MPI
• Percutaneous transluminal coronary angioplasty (PTCA) or stent placement within 3 days prior to MPI
• Current ventricular tachycardia, atrial fibrillation, atrial tachycardia, or atrial flutter
• Current history of exacerbated COPD or asthma
• Known hypersensitivity or contraindication to regadenoson or aminophylline
• Use of caffeinated substance, dipyridamole-containing medication, aminophylline, or xanthines containing medication (e.g. theophylline) within the 12 hours prior to Lexiscan administration.

Where it is running

• Saint Louis University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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