Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

Recruiting now

Conditions studied: Pediatric Patients Treated With Radiation Therapy

In brief

In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that currently receives radiation and better compare the short-term and long-term benefits of different types of radiotherapy. The data collected from this study will help facilitate research on radiation therapy and allow for collaborative research. The PPCR will collect demographic and clinical data that many centers that deliver radiation therapy already collect in routine operations.

Key facts

Study ID

NCT01696721

Run by

Massachusetts General Hospital

People needed

5000

Starts

2012-07-01

Expected to finish

2028-12-01

Last updated by the study team

2026-05-14

Who can join

Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University Health Network - Princess Margaret Hospital — Toronto, Ontario, Canada (enrolling)
• California Protons Cancer Therapy Center — San Diego, California, United States (enrolling)
• University of California San Francisco — San Francisco, California, United States (enrolling)
• University of Florida Health Proton Therapy Institute — Jacksonville, Florida, United States (enrolling)
• Emory University — Atlanta, Georgia, United States (enrolling)
• Northwestern Medicine Chicago Proton Center — Warrenville, Illinois, United States (enrolling)
• Maryland Proton Treatment Center — Baltimore, Maryland, United States (enrolling)
• Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)
• Mayo Clinic — Rochester, Minnesota, United States (enrolling)
• Washington University — St Louis, Missouri, United States (enrolling)
• ProCure Proton Therapy Center- New Jersey — Somerset, New Jersey, United States (enrolling)
• New York Proton Center — New York, New York, United States (enrolling)
• State University of New York Upstate Medical Center — Syracuse, New York, United States (enrolling)
• University of North Carolina — Chapel Hill, North Carolina, United States (enrolling)
• The Ohio State University — Columbus, Ohio, United States (enrolling)
• Cincinnati Children's Proton Therapy Center — Liberty Township, Ohio, United States (enrolling)
• Oklahoma Proton Center — Oklahoma City, Oklahoma, United States (enrolling)
• ProCure Proton Therapy Center- Oklahoma — Oklahoma City, Oklahoma, United States (enrolling)
• University of Pennsylvania - Roberts Proton Therapy Center — Philadelphia, Pennsylvania, United States (enrolling)
• Stanford University — Palo Alto, California, United States (enrolling)
• MD Anderson Cancer Center — Houston, Texas, United States (enrolling)
• Texas Center for Proton Therapy — Irving, Texas, United States (enrolling)
• University of Utah — Salt Lake City, Utah, United States (enrolling)
• University of Washington- Seattle Cancer Care Alliance — Seattle, Washington, United States (enrolling)
• Royal Adelaide Hospital — Adelaide, South Australia, Australia (enrolling)

Full record on ClinicalTrials.gov

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